| 1. | Effects of exercise on myosin and convertion of muscle fiber types 运动训练对肌球蛋白重链及肌纤维转型的影响 |
| 2. | This is important in attempting to use antibodies as anti - tumor reagents , for example 基因为日本血吸虫单克隆抗独特型抗体np30轻链和重链可变区基固。 |
| 3. | Alpha - chain protein was not demonstrated in the patient ' s serum , urine , diluted duodenal juice , and jejunal biopsy tissue 但在病人的血清、尿液、十二指肠液、和空肠切片组织中无法显示出甲种重链蛋白质。 |
| 4. | The purity was detected by sds - page , and only igg ' s heavy chain and light chain protein tope were showed up . the activity of igg was tested by technique of immune credeschs gold 用sds - page进行igg的纯度检验,电泳结果出现两条蛋白带,是igg的重链和轻链,说明纯化的程度较高。 |
| 5. | Recent studies have indicated the existence of dynein heavy chain and light chain in higher plants , but no data about dynein intermediate chain in higher plants have been reported 近来的研究表明在高等植物细胞中存在细胞质力蛋白的重链和轻链,但力蛋白中间链在高等植物细胞中还未见报道。 |
| 6. | New york ( reuters health ) dec 19 - lactobacilli transformed to carry heavy - chain antibody fragments appear to protect against rotavirus infection , swedish investigators report in the december 1st issue of the journal of infectious diseases 纽约(路透社健康版) 12月19日瑞典研究人员首次在12月传染病杂志上发表报告称:经改造携带重链抗体片断的乳酸菌有抗轮状病毒感染的作用。 |
| 7. | However , continued injection of humans with antibodies made in another species eventually leads to the production of antibodies against the foreign antibodies . this problem may now be circumvented by immunizing mice that have been transfected with large segments of the human immunoglobulin loci so the mice actually produce human antibodies V 。基因全长357hp ,属鼠免疫球蛋白重链第i亚类,由种系基因v 、 dspz 8与jh4重排而来,编码119个氨基酸残基。 |
| 8. | The library was rescued with phage m13k07 in order to display scfv on the surface of the phage and to form the recombinant phage antibody library . one of positive scfv clones , named pcsal , was selected with phage - elisa after panning and screening by bull sperm three times . scfv fragment , amplified from pcsa1 , was ligated to pmd18 - t vector for sequencing analysis 取阳性重组噬菌体抗体克隆株pcsa1 , pcr扩增其scfv基因,筛选重组子进行序列测定,发现其序列符合小鼠抗体基因的一般特征,并且与几株抗磷酸胆碱的抗体重链和轻链可变区序列的同源性达80以上;推测pcsa1scfv针对的抗原是磷酸胆碱类物质。 |
| 9. | Elevation of intracellular calcium ions may be partly induced by increased influx through sarcolemma l type - calcium channels . intracellular calcium elevation , on one hand , would activate calpain , a calcium - dependent cysteine protease that degrade the myofibrillar proteins and cause muscle atrophy ; on the other hand , result in activation of calcineurin which enhance the activity of mhc i promoter and inhibit a shift of mhc isoforms from slow to fast in soleus 这样,可能使得萎缩比目鱼肌细胞内钙离子水平升高,细胞内钙离子静息浓度的增加一方面激活calpain ,增加收缩蛋白的降解,使肌肉萎缩;草四军医大月卜祠成士学位论文另一方面通过激活钙调神经磷酸酶,增加快型mhc基因的表达,使骨骼肌肌球蛋白重链( mhc )发生由慢型向快型的转化。 |
| 10. | Thus , immunologists have sought smaller molecules with the antigen - recognition capability of antibodies . the variable domains of the heavy ( h ) and light ( l ) chains are sufficient for antigen recognition but the non - covalent complex of the two variable domains ( fv ) is unstable . it is possible to genetically engineer a single - chain fv ( scfv ) with the h chain v region connected to the l chain v region via a 15 amino acid linker composed of serine and glycine amino acid residues 二、日本血吸虫单克隆杭独特型抗体np30的单链狐( scf )的构建、表达及对balbic小鼠诱导保护性作用研究l 、日本血吸虫单克隆杭独特型抗体np0的单链抗体归cfv )的构建、表达通过pcr方法体外扩增并经测序验证的重链、轻链可变区( vh 、 vl )基因先后重组入原核表达质粒ptha90相应的位点上,中间通过一连接肽( gly在er ) 。 |