| 1. | The network is teaching its operatives how to produce ricin and other poisons
这个网络教授它的人员如何制作蓖麻毒素和其他毒药。 |
| 2. | Ricin enters the cells by receptor - mediated endocytosis , followed by translocation across the membranes of intracellular compartments
蓖麻毒素具有强烈的细胞毒性，具有抗肿瘤的应用前景。 |
| 3. | Police in las vegas , nevada , are investigating the discovery of what they said is the deadly poison ricin in a hotel room
警方正在对在内华达州拉斯维加斯一宾馆房间内发现的致命毒药蓖麻毒素展开调查。 |
| 4. | It is estimated that the protein , ricin , found in the castor bean plant is as much as 6 , 000 times more poisonous than cyanide
据估计，蓖麻子豆中找到的一种名为蓖麻毒素的蛋白质，所含的毒性物质比氰化物多出了6000倍。 |
| 5. | Our goal is to express the ricin a chain ( rta ) and its modification rta - kdel ( er - retrival signal ) in escherichia coli
本论文旨在研究蓖麻毒素a链蛋白( rta )及其修饰体rta - kdel (内质网保留信号肽)在大肠杆菌中的表达。 |
| 6. | Ricin toxin ( rt ) is a plant toxin isolated from the seeds of ricinus communis . it is one of the most powerful plant toxin discovered
蓖麻毒素( ricintoxin ， rt )是从大戟科植物蓖麻( ricinuscommnnis )的种子中提取的一种毒性蛋白，具有强烈的细胞毒性。 |
| 7. | [ backgrounds ] many plants produce toxic proteins known as ribosome inactivating proteins ( rips ) whose functions mainly serve as a defensive tool against invasion of other organisms
[目的]蓖麻毒素是一种典型的植物毒蛋白，由a 、 b两条链通过二硫键结合。 |
| 8. | We know from iraq ' s past admissions that it has successfully weaponized not only anthrax , but also other biological agents , including botulinum toxin , aflatoxin and ricin
我们从伊拉克过去承认的事实中了解到，它已不仅成功地将炭菌病毒制武器化了，而且将包括肉毒菌毒素、黄曲霉毒素和蓖麻毒素等生物制剂武器化了。 |
| 9. | Because expressed in escherichia coli , ricin a chain is not degraded easily for its non - glycosylation . our experiments lay a foundation for the researches that rta conjugates a monoclonal antibody to synthesize immunotoxins and the immunotoxins are used for cancer - targeted therapy
蓖麻毒素a链在大肠杆菌中表达，因无糖基化修饰，克服了进入体内后被迅速降解的缺点，为进一步与单链抗体基因嵌合表达形成单链免疫毒素，对肿瘤细胞进行导向治疗研究奠定基础。 |
| 10. | Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin , diphtheria toxin , shiga toxin and pseudomonas exotoxin ( pe ) . a number of these toxins are transported to trans - golgi network ( tgn ) , and in many cases such transport to the tgn is required for the translocation and cytotoxicity . in deed , 5 % of the ricin endocytosed by cells has been shown to reach the tgn
蓖麻毒素进入细胞的机理不甚明了，一般认为是rtb先与细胞膜受体结合，主要经过受体介导的内吞作用进入吞噬体，然后沿着内体、高尔基体、内质网等逆向分泌途径，有序地运输到内质网，最后从内质网转位进入细胞浆，在胞浆内攻击核糖体，从而抑制蛋白质的合成，导致细胞死亡。 |
