Conclusion : the " four - step method " for extraction of c . albicans proteins is an effective approach to study c . albicans membrane proteome arid lays a foundation for further investigation of the mechanisms of antifungal agents and drug resistance in c . albicans 结论:四步法提取白念珠菌总蛋白质是研究白念珠菌蛋白质组的有效方法,为进一步研究白念珠菌耐药机制以及抗真菌药物作用机制奠定基础。