Gordon gj et al recently described the cellular responses and time course for liver regeneration after ph in rats with retrorsine - induced hepatocellular injury . this model involves the prior administration of the dna - binding pyrrolizidine alkaloid retrorsine to rats blocking native hepatocyte proliferation 最近, gordongj等报道了一种新的肝脏再生反应,他们首先用倒千里光碱( retrorsine )抑制大鼠成熟肝细胞的再生能力,然后通过肝2 / 3切除施以肝脏强大的再生刺激。