| 1. | The method of making dna vaccine is a new technology that did not come to being until 1990
Dna疫苗是90年代发展起来的一项新型疫苗技术。 |
| 2. | Nucleic acid vaccine is one new kind of vaccine developed from the 90 ' s of 20th century
摘要核酸疫苗是20世纪90年代初发展起来的一种新型疫苗。 |
| 3. | As a result , developing a safe and effective fmdv vaccine has become a research priority
目前研究人员通过基因工程方法开发口蹄疫安全的新型疫苗成为研究的热点。 |
| 4. | So gaining vp7 gene and its expressing product is key to the preparaion of the new type vaccine and specific diagnosis anigen
因此，该基因的克隆及表达，对于制备新型疫苗和特异性诊断抗原具有重要意义。 |
| 5. | The high conservative main antigenic protein vp3 of gpv provided the access to producing the new type vaccines and diagnostic agent
Gpv主要免疫原性蛋白vp3的高度保守性给新型疫苗及分子诊断试剂的研制提供了思路。 |
| 6. | Up to now , there are still some infectious diseases that cannot be prevented effectively . the traditional vaccines are mostly less safe or efficacious , driving efforts to develop vaccines of new generation
迄今为止，许多传染性疾病尚未得到有效防治，现行的灭活疫苗或弱毒疫苗等传统疫苗或免疫效力低下，或存在安全性问题，促使人们开发安全有效的新型疫苗。 |
| 7. | But ib attenuated vaccine has many defects , such as the possibility of contamination of foreign and vertical transmissible pathogens , and the virulent recovery of vaccine virus . therefore , exploring the safe and efficient new vaccines has become the hotspot in the research of ib control
由于活疫苗存在外源性或垂直传播性病原污染、毒力返祖等缺陷，开发安全、有效的新型疫苗是ib控制的研究重点。 |
| 8. | Genetic vaccine is quite different in structure from traditional ones . the experiments show that delivery of genetic material into an animal ' s cells can trigger some synthesiztion of the encoden proteins as well as of antibodies targeted against those proteins
核酸疫苗是将编码某种抗原蛋白的外源基因插入某种表达载体中并直接导入的动物体内，表达抗原蛋白，并诱导宿主产生对该抗原蛋白免疫应答的革命性的新型疫苗。 |
| 9. | Antigens from infectious bacterial or viral diseases have been introduced into plants . so introducing vp7 gene into tomato to develop edible plant vaccine of rotaviruses would change the traditional means of production of vaccines and the cost of vaccine production would be reduced greatly
因此，将vp7基因导入番茄，获得具有免疫原性的轮状病毒植物口服疫苗，将为防治轮状病毒引起的小儿腹泻提供新型疫苗，具有潜在的社会和经济意义。 |
| 10. | All the result showed that ndv f48e9 strain has its own speciality compared with other five ndv strains , and there were many difference between velogenic strains and lentogenic strains . so the infectious cdna of rnesogenic strains and lentogenic strain was far from enough to understand the replication , pathogenicity of ndv and the interaction between ndv and host cells , and the infectious cdna of velogenic strains ( eg . . f48e9 ) was required to explain the relationships between structure and function
本研究成功地获得了ndvf48e9 t因组的核昔酸序列，并构建了表达ndvf48e9基因组cdna的低拷贝表达载体休f48e9 ，为构建新城疫病毒强毒株f48e9株的感染性cdna奠定了物质基础，进一步研究ndv的生物学特性、结构与功能的关系；进一步探讨影响ndv毒力的因素、以及研制新型疫苗载体提供了可靠保证。 |
