| 1. | The effects of erythropoietin on quality of life in uremic patients in maintenance hemodialysis
重组人红细胞生成素对尿毒症血液透析患者生活质量的影响 |
| 2. | Preparation and characterization of non - agglutinating mabs against membrane antigen on human erythrocytes
抗人红细胞膜抗原非凝集型单克隆抗体的研制及特性鉴定 |
| 3. | Relation between environmental pollution caused by free sio2 dust and lipid peroxidation in erythrocyte membrane in human
2环境污染与人红细胞膜脂质过氧化损伤 |
| 4. | Patients received 20 , 000 iu of epoetin alfa subcutaneously every 2 wk for up to 27 wk , with dosage adjustments permitted after 4 wk of treatment
病人每两周接受1次重组人红细胞生成素皮下注射，直到第27周，在用药第4周后允许对用药量进行调整。 |
| 5. | 9 stockenhuber e , kurz rw , geissler k , et al . recombinant human eryt hropoietin activates a broad spectrum of progenitor cell . kidney int 1990 ; 37 ; 150 - 6
8蒋建平，张训，侯凡凡.重组人红细胞生成素对血透患者单个核细胞分泌功能的影响.中华肾脏病杂志1996 ； 12 ： 131 - 3 |
| 6. | This open - label , multicenter , single - arm study investigated the efficacy of administration of 20 , 000 iu of epoetin alfa once every 2 wk as initiation therapy in these patients
这个标签公开，多中心，单一目的的试验观察在起始治疗阶段每两周注射1次重组人红细胞生成素20 , 000iu的效果。 |
| 7. | There are limited data suggesting that initiation of epoetin alfa at extended dosing intervals of every 2 , 3 , or 4 wk may be efficacious for treating anemia in patients who have chronic kidney disease and are not on dialysis ( ckd - nod )
有限的资料显示：扩大初始的给药间隔时间到2 ， 3 ，或者4周，对应用重组人红细胞生成素治疗慢性肾脏病未透析患者( ckd - nod )的贫血是有效的。 |
| 8. | Therefore the hybrid - hybridoma can secrete not only bispecific antibody but also anti - human rbc type a monospecific antibody and probably anti - p24 monospecific antibody . the mixed antibodies purified by ammonium sulfate is further purified by p24 affinity chromatography . the unsp
这样，分离出双特异性抗体，并证实杂交杂交瘤除分泌抗p24和人红细胞的双特异性抗体外，还分泌抗p24单特异性抗体和抗人a型红细胞单特异性抗体。 |
| 9. | The ascites fluid antibody purified by 33 % ammonium sulfate is further purified by chromatography . the p24 affinity chromato - graphic column done to purify the bispecific antibody is in the brcn activated sepharose 4b . after washing the unspecific proteins , change the washing buffer and the anti - p24 / anti - human rbc type a bispecific antibody and the anti - p24 monospecific antibody are gained respectively
方法是先用硫酸绥盐析，再过亲和层析柱，即33饱和硫酸按沉淀后，透祈过夜，上p24抗原做配体的滨化氰活化的sepharose4b柱，流洗掉杂蛋白和抗人红细胞单特异性抗体后，再洗脱并收集双特异性抗体。 |
| 10. | 2 - e4 - a and 82 - 6 are hybridized during their log growing time , and the hybrid - hybridomas are cloned for 3 times and produce 6 hybrid - hybridoma cells . the chromatosome of hybrid - hybridoma 3 - hu and hybridoma 2 - e4 - a and s2 - b are counted , and the antibody of ascites fluid or culture supernatant of 3 - hn is prepared . the positive clones are detected by three methods at the same time : rbc agglutination for monospecific anti - human rbc type a antibody , indirect elisa for anti - p24 antibody , and rbc solid - phase adherence for bispecific antibody
选其中一株3 - h _ ( 11 )做杂交-杂交瘤细胞染色体计数，同时计数两母株2 - e _ 4 - a和s _ 2 - b的染色体数：制备腹水型和上清型抗体，用三种方法同时检测其中的双特异性抗体、单特异性抗人红细胞抗体和抗p24抗体，即红细胞固相吸附法测双特异中文摘要性抗体，红细胞凝集试验测单特异性抗人a型红细胞抗体，间接elisa法测抗p24抗体；用腹水型抗体做耐热性及耐冻融实验。 |
