| 1. | The scrapie agent in sheep may be similar to viroids .
绵羊的搔痒病因子可能也是类病毒。 |
| 2. | Scrapie , creutzfeld - jakob and bse are among the most unusual diseases known to medical research
羊痒病、克雅氏病和疯牛病是医学研究中最罕见的疾病之一。 |
| 3. | The holes were unmistakably like scrapie , the sheep sickness that was the first documented spongiform encephalopathy
这些小洞与羊搔痒症极像，羊搔痒症是一种发生在羊身上的病变，是最早有记录的海绵状脑病。 |
| 4. | Preious work has shown that mice with their prion gene knocked out remain healthy , and when inoculated with scrapie are protected against the disease1
先前的工作已经告诉我们，被敲除普粒子基因的老鼠仍然健康，并且当嫁接羊瘙痒病的时候它们能够抵御疾病。 |
| 5. | The prototypic prion disease found is scrapie . the epidemic of bse in england and the newly found vcjd in human attracted more attention to prion diseases and the disease - causing proteins
羊瘙痒症是最早发现的朊蛋白病，而疯牛病在英国的流行以及新近发现的新变种的人类雅各布氏病引起研究者们对朊蛋白疾病及其致病蛋白的更大关注。 |
| 6. | If a drug could be made that inhibits this fragmentation process , it could substantially slow the spread of prions , which cause mad cow disease and scrapie in animals and , in rare cases , creutzfeldt - jacob disease and kuru in humans
药物可阻滞这些蛋白裂解片段过程，从而持久的减慢朊病毒传播，包括疯牛病和绵羊疯痒病和一些人类罕见疾病克-雅二氏病和库鲁病等疾病的传播。 |
| 7. | The most recent public service agreements on the british treasury website , for example , spell out government commitments to make schoolchildren do more physical education , increase participation in the arts and reduce scrapie in sheep
例如，最近在英国财政部网站公布的公共服务协议，阐明了政府的承诺，要增加中小学的体育课，鼓励人们参与艺术活动，并减少羊搔痒症的发病率。 |
| 8. | There exist two prion protein forms , the pathological form , prpsc ( sc stands for scrapie ) , and normal cellular form , prpc ( c stands for cellular ) . these two proteins have the same amino acid se quence , the only difference lies in conformation
研究得知朊蛋白有两种形式，一种为致病形式( prpsc ， sc是瘙痒症的缩写) ，另一种为组织内正常存在的细胞形式( prpc ， c是细胞型的缩写) ，这两种蛋白在一级结构的氨基酸序列相同，仅构象有不同。 |
