The genetic polymorphisms due to mutations in the methylene tetrahydrofolate reductase gene may increase the risk for ntds 亚甲基四氢叶酸还原酶基因突变导致的遗传多态现象可增加神经管缺陷( ntd )发生的危险性。
3.
The c677t and the a1298c mutations are associated with elevated maternal homocysteine concentrations and an increased risk for ntds in fetuses C677t和a1298c突变使母体同型半胱胺酸水平升高，增加神经管缺陷发生的危险性。
