The expression of gpr78 displayed the levels in tendency to decrease from telencephalon to metencephalon during embryonic period . this suggested grp78 play an important role in the early morphogenesis of brain . it may be a positio 3 . gr脚8 、 gr即4在脑发育过程中的不同表达模式提示存在尚未被认识的与upr机制不同的内质网分子伴侣表达调控机制。
