| 1. | Determination of lovastatin level in human plasma and lovastatin capsules bioavailability in healthy volunteers using hplc - ms
法检测洛伐他汀血药浓度及其生物利用度 |
| 2. | Also , the anti - tumor function of lovastatin hi vivo was assessed utilizing monascus mber containing lovastatin
研究结果显示， lovastatin能有效抑制人肺癌d6细胞株的增殖，并诱导其凋亡。 |
| 3. | Adding exogenous cholesterol can partly invert the lovastatin - mediated growth - inhibition and induced apoptosis , indicating that cholesterol maybe involved in the regulation mechanism of lovastatin
外源性胆固醇能部分逆转lovastatin作用的细胞增殖抑制及细胞凋亡，表明胆固醇参与了lovastatin对细胞生长的调控过程。 |
| 4. | Methods : the patients with carotid atherosclerotic plaques were divided into tiaozhi capsule group and lovastatin group and treated for 6 monthes , compared the carotid intima - media thickness and plaques area
方法：将颈动脉有软斑块患者分为调脂胶囊组和洛伐他汀组治疗6个月，比较两组患者治疗前后颈动脉内中膜厚度和斑块大小的变化。 |
| 5. | The anti - tumor effect of monascus mber containing lovastatin in vivo was not significant hi the si80 tumor modle . finally , the mechanisms of growth - inhibition and induced apoptosis with lovastatin were disccused on the basis of the results obtained hi the present study
与对照组相比， 2红曲组的抑瘤率为9 . 63 ， 10红曲组的抑瘤率达18 . 19 。 |
| 6. | Hi the precent study , the effect of lovastatin on human lung cancer d6 cell was examined and the role of cholesterol involving in the process of growth - inhibition and induced apoptosis of cell treated with lovastatin was investigated
本研究以人肺癌d6细胞株为实验材料，研究了lovastain对其生长的影响，以及胆固醇在lovastatin对细胞生长的调控中所起的作用。 |
| 7. | Lovastatin , the 3 - hydroxy - 3 - methylglutaryl - coenzyme a ( hmg - coa ) reductase inhibitor , is generally applied in the treatment of hypercholesterolemia . it is recently demonstrated that lovastatin inhibits proliferation of tumor cells and triges apoptosis
近年来已有研究发现， lovastatin能够有效抑制多种肿瘤细胞株增殖并诱导细胞凋亡，关于lovastatin在肿瘤抑制机理及其肿瘤治疗效应研究已经受到极大关注。 |
