Many nuclei have become pyknotic ( shrunken and dark ) and have then undergone karorrhexis ( fragmentation ) and karyolysis ( dissolution ) 细胞核固缩（缩小和深染） ，接着核碎裂（形成碎片）和核溶解（溶解消失） 。
2.
Ultrastructurally , karyopyknosis and karyolysis occured in lymphocytes , and the mitochondria , rough endoplasmic reticulum of lymphocytes in the immune organs were damaged . the nucleus were deformity , the rmtochondrial and rough endoplasmic reticulum were swelling , and the ribosomes were shed in reticular cells of thymus in zinc - deficient ducklings 超微结构显示缺锌组淋巴细胞核固缩或溶解，线粒体、粗面内质网受损；胸腺网状细胞核受损，粗面内质网扩张，线粒体肿胀、嵴断裂。
