In immunocompetent hosts , jc virus remain dormant in nuclei of rare scattered glial cells in brain and spinal cord parenchyma 在免疫功能正常的宿主, jc病毒主要存在于脑、脊髓的少数神经胶质细胞的核内。
2.
Although the antigen test for cm infection is sensitie and specific in immunocompromised patients , it has limited sensitiity in an immunocompetent host 虽然cm感染的抗原试验对于免疫缺乏的病人来说具有灵敏性和特异性,但对于具有免疫活性的病人则灵敏性不足。
3.
These data showed that the chimerism were specially tolerant to donor xenoantigens in skin grafting and mixed lymphocyte reaction ( mlr ) assays , however were still immunocompetent to mhc - disparate third party c57bl / 6 mouse . in the second experiment , mice of group b appeared with variant degree of wasting , diarrhea , fur losing , and all died within 15 days . pathologic changes of liver and intestine were inflamming cells infiltrating and necrotizing 肝、小肠切片均有明显病理改变,主要表现为肠粘膜部分脱落、坏死和炎性细胞浸润,肝实质内有灶性淋巴细胞及多形细胞浸润,并可见局灶性坏死,两者均符合gvhd病理改变。