| 1. | Artificial immune algorithm based on idiotypic - network dynamic model 基于独特型网络动力学模型的人工免疫算法 |
| 2. | Tcr idiotypic dna vaccine may generate anti - idiotypic immunity against the tumor 应用tcr独特型dna疫苗有可能激发抗肿瘤独特型免疫反应。 |
| 3. | Calcium nanoparticles as vaccine adjuvant of anti - idiotypic antibody for schistosomiasis 1 钙纳米颗粒作为血吸虫病抗独特型抗体疫苗佐剂的研究1 |
| 4. | Results : we obtained the recombinant plasmid containing idiotypic tcryv1 fragment of the jurkat cell line 结果:本文构建了jurkat淋巳媲细胞系独特型tcrvvidna重组载体pcdna 。 1cry 。 |
| 5. | This study was undertaken to investigate the anti - tumor immuneologic effects induced by tcr idiotypic dna vaccine on balb / c mice 本文观察tcr独特型dna疫苗诱导balb c小鼠抗肿瘤免疫反应的情况。 |
| 6. | Anti - idiotypic antibody np30 was confirmed with protective immunity of both anti - infection and anti - pathology and may act as a vaccine candidate for schistosomiasis japonica 证南京医科大学博士学位论文明抗独特型抗体np30分子具有较好的抗感染免疫和抗病免疫功效,可作为日本血吸虫病疫苗候选分子。 |
| 7. | 1 determine whether calcium nanopart i c i es can act as a vaccine adjuvant of anti - idiotypic antibody for schistosomiasis first , we prepared calcium nanaparticles ( ca ) by physical method , its diameter is 300 - 800 nm 1探索钙纳米颗粒ca作为血吸虫病抗独特型抗体疫苗佐剂的可行性应用物理方法制胸纳米颗粒ca ;颗粒直径为3o0一8o0m 。 |
| 8. | Guan xiaohong ( 1991 ) established a cell line of the monoclonal anti - idiotypic antibody ( anti - id ) np30 of schistosoma - 6 - japonicum , whose isotype was identified to be igm and which was testified to be internal image of gaa 分别以日本血吸虫单克隆抗独特型抗体wbo的杂交瘤细胞株总基因组dna和其提取rna进行rticr合成的cdna第一链为模板,扩增v 。 、 v 。 |
| 9. | Amplification , cloning and sequence analysis of the light chain and the heavy variable region genes of monoclonal anti - idiotypic antibody np30 of schistosoma japonicum to amplify and sequence the gene of the heavy chain and the heavy chain of anti - idiotypic monoclonal antibody np30 of schistosoma japonicum 2 、日本血吸虫单克隆抗独特型抗体np30的单链抗体kcfv )对balb c小鼠诱导保护性作用研究为了研究日本血吸虫抗独特型抗体np30单链抗体作为日本血吸虫病 |
| 10. | The expressive gene fragment was 333bp long . analyses of the tcr y fragment shpwed that it contained three epitopes . it was showed that specific anti - idiotypic antibody could be found since four weeks after the first immunization and came to the climate on the sixth week . the antibody titers of the same time were higher in group pcdna3 / tcr y - il - 2 than in group pcdna3 / tcr y ( po . 01 ) . the highest antibody titer was 1 : 640 in the group pcdna3 / tcr y - il - 2 , whereas the highest was 1 : 160 in the group pcdna3 / tcr y . there were mrna expression in skeletal muscle cell could be found in group pcdnas / tcr y and group pcdna3 / tcr y - il - 2 on fifth day after inoculation 用tcryvi独特型dna重组载体作为疫苗免疫小鼠,结果表明pcdna3汀cry组及pcdna3厅cry ? il ? 2组小鼠1血肩中全部产生了特异性抗独特ffo抗体,抗体滴度在第4周开始增高,第6周时达到高峰。在同一取血时间, w儿1 ry一几一二组小鼠抗体滴度均高于pcdna3 tcry组( p 0 1 ) 。 pcd a3 tcry组小鼠抗体滴度最高达1 : 16小pc 。 |