Protective effects of diazoxide - preconditioning on myocardial ischemia - reperfusion injury of rats 纳洛酮在大鼠肠缺血再灌流致肺损伤中保护作用的初步研究
2.
Another interention is the induction of ? - cell " rest " by selectie actiation of atp - sensitie k + ( katp ) channels , using drugs such as diazoxide 另一种方法是选用atp敏感的钾离子通道激动剂(如氯甲苯噻嗪)诱导静止的细胞。
3.
Another intervention is the induction of ? - cell " rest " by selective activation of atp - sensitive k + ( katp ) channels , using drugs such as diazoxide 另一种方法是选用atp敏感的钾离子通道激动剂(如氯甲苯噻嗪)诱导静止的细胞。
4.
The management of these patients included medication to maintain normoglycemia ( octreotide , diazoxide and glucagons ) and feedings with a gastronomy tube 这些患者的治疗包括服用药物(奥曲肽,二氮嗪及胰高血糖素)以维持正常血糖以及胃管喂养。
5.
These data suggested that following hypoxia / reoxygenation , over - activity of bkca channels may mediate cultured hippocampal neuronal apoptosis induced by hypoxia / reoxygenation via activation of caspase - 3 X现diazoxide或valinomycin均可诱导正常培养的神经元凋亡及激活caspase上。上述结果表明缺氧复氧可能引起bkc 。
6.
Furthermore , k + ionophore valinomycin and k + channel opener diazoxide alone induced neuronal apoptosis and caspase - 3 activation . besides , katp channel blockers tolbutamide and glybenclamide also showed neuroprotective effects and decreased caspase - 3 activation after hypoxia / reoxygenation . while the role of katp channels in neuronal apoptosis is not clear 为进一步证实钾通道在缺氧复氧诱导的神经元凋亡中的作用,我们采用了钾通道开通剂100pmdiazoxide及钾离子载体50nmvallnomycln 。