The animal experiment is carried out in the first hospital of shanghai through renovating the injured nerve of the rats . four projects are used in this experiment : the conduits coated with pgla , the conduits coated with chitosan , the conduits coated with chitosan adding bridge - yarn and self - nerve migration . after 12 weeks , we observe and analyze the thickness of marrow theca , the diameter of axone , the density of regeneration nerve and then do electromyography and statistics analyzing , finding out that the third conduits have the best recovering effects on the injured nerve , close to the self - nerve migration 因此我们选用加筋结构神经导管进行动物实验。本课题动物实验在上海市第一人民医院进行，分别通过加筋结构涂pgla导管、加筋结构涂甲壳胺导管、加筋结构涂甲壳胺并加载缝芯线导管和自体神经移植四种方案对大鼠进行损伤神经修复实验。在术后12周对四种方案再生神经的髓鞘厚度、轴突直径、数量密度进行观察分析，并进行肌电图检测和统计学分析。
