Recently the coupling of ims equipped with electrospray ( esi ) or matrix - assisted laser - desorption ( maldi ) ion sources to mass spectrometry ( ms ) has extend its application to the biomedical area 近年来,离子迁移谱技术与电喷雾和基质辅助解吸附等离子化技术的结合,以及与质谱技术的联用,使得该技术的应用迅速拓展到生物医学领域。