The early embryo were made into a series of continuous section slides by tissue cutting . the sections were stained by hematoxylin and eosin ( h & e ) staining and then the development of internal organs such as heart in early embryos was observed by microscope . we found that there is certain relationship between external and internal malformation 同时我们收集人类药物流产的早期胚胎,观察发现胚胎畸形占17 . 86 % ,早期致死占32 . 54 % ;采用组织切片技术将胚胎制成一系列石蜡连续切片,染色后显微观察畸形和正常的早期胚胎内部心脏等器官的发育情况,发现胚胎外部畸形与体内畸形存在一定关联,对此我们将做进一步的研究。