English translation for "烷化剂"
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- alkyl agent
alkylagents alkylaing agent alkylating agents chloronaftina
Related Translations:
烷: 名词[化学] (有机化合物的一类) alkane
- Example Sentences:
| 1. | The hydrocarbon diperchlorate products have utility as detonatable sensitizers for explosives and alkylating agents . 二过氯酸烃基酯产物可用作起爆药的敏化剂及作为烷化剂。 | | 2. | Evidence - based treatment of alkylating agents for idiopathic membranous nephropathy with nephrotic syndrome 烷化剂在1例特发性膜性肾病合并肾病综合征的循证应用 | | 3. | Mms , a kind of dna - damaging agent , predominantly methylates ring nitrogens of pyrine , leading to dna double - strand breaks , point mutation and so on 甲磺酸甲酯( methylmetbanesulfonate , mms )是一种能够损伤dna的烷化剂,主要使dna嘌呤碱基上的o 、 n甲基化,造成dna双链断裂、点突变。 | | 4. | Therefore , it is important to study the profiles of gene expression , which will help understand the global cellular stress responses to chemical carcinogens , and further elucidate the mechanisms of nontargeted mutagenesis 所以,从整体上研究烷化剂作用后细胞基因表达谱改变,对于了解化学致癌物诱发的哺乳动物细胞应激反应的全貌和揭示非定标性突变的发生机制具有非常重要的意义。 | | 5. | In contrast , most mature somatic cells in human tissues express undetectable or low telomerase activity , implying the existence of a stringent and negative regulatory mechanism . in this study , we report the effects of cisplatin on telomerase activity in human ovarian cancer cells . the special relationship between activity and cancer has a important application value 顺铂( ddp )是卵巢癌化疗中最有效的基础药物之一,它是一种类烷化剂的抗肿瘤药物,为细胞周期非特异性药物,可作用细胞周期的任一时相,利于临床的联合用药,但由于ddp的诸多毒副作用及卵巢癌细胞易产生对其耐药性,常使化疗效果不满意。 | | 6. | Monofunctional alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng ) is a widely spread environmental mutagen and carcinogen that targets dna and proteins to generate adducts . among the adducts , o6 - alkyl guanine is the predominant mutagenic lesion because of its mispairing properties , which can eventually lead to chromosomal aberrations , point mutations , and cell death . this lesion also appears to be involved in tumor initiation , particularly in gastric carcinogenesis 单功能烷化剂n -甲基- n -硝基- n -亚硝基胍( mnng )是一种在环境中广泛存在的化学诱变剂和致癌剂,它能和dna及蛋白质等生物大分子形成加合物( adduct ) ,其引起的与突变有关的主要dna损伤类型是o ~ 6 -甲基鸟嘌呤,这种损伤与肿瘤尤其是胃癌的发生密切相关。 | | 7. | In our laboratory , a unique mutation detection system using a shuttle vector plasmid has been established to demonstrate that a low concentration of mnng ( 0 . 2 m ) can induce nontargeted mutation in mammalian cells : the mammalian cells were exposed to 0 . 2m mnng for 2 . 5h , then a shuttle plasmid pz189 carrying supf trna gene was transfected into cells after 24h culture . we found a 5 - fold higher mutation frequency of the plasmid replicated in pretreated cells than the spontaneous mutation frequency of the plasmid replicated in control cells . this kind of mutation did not occur immediately after mnng exposure 我们实验室曾用一特殊的突变检测系统,直接证明dna损伤剂可在哺乳动物细胞诱发非定标性突变:首先用低浓度( 0 . 2 m )的短寿烷化剂mnng (半寿期为1 . 1hr )处理细胞2 . 5h后,继续培养24h ,将重组有用作突变检测的靶基因supftrna基因的穿梭质粒pz189转入细胞复制,发现在未受致癌物直接攻击的穿梭质粒中有较自发突变率高5倍以上的靶基因突变。 |
- Similar Words:
- "烷化法" English translation, "烷化芳香烃" English translation, "烷化工厂" English translation, "烷化过程" English translation, "烷化环烷" English translation, "烷化剂误修复" English translation, "烷化剂诱变" English translation, "烷化聚合物" English translation, "烷化硫代双苯酚" English translation, "烷化硫代双酚" English translation
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