| 1. | Research progress on prion and prion disease therapy
朊病毒和朊病毒疾病治疗的研究进展 |
| 2. | Prion diseases are always fatal , often , however , not until months after the outbreak of the disease
致病性的朊病毒蛋白质在脑中沉积并损伤脑组织。 |
| 3. | They believe that infectious prions might wake viruses that lie dormant in the dna of an uninfected cell
他们相信感染朊病毒可能唤醒健康细胞内其他病毒沉睡的dna 。 |
| 4. | That infectious prions cause rubbish to accumulate in brain cells may not be the only way in which they cause damage
而朊病毒引起脑细胞垃圾的堆积也许不是灾难被引起的唯一方式。 |
| 5. | The findings are exciting , researchers say , because they might reeal a way to control the spread of prions through drug interention
消息振奋人心，研究者们称这样可以通过药物干预控制朊病毒播散。 |
| 6. | Then she added an antibody that cleared the cells of prions but left the ubiquitins , the proteasome and the waste proteins in place
然后她又向细胞注射了可清除朊病毒而不伤及降解酶和水解酶与废物的抗体。 |
| 7. | Although these tests show that prions can force the waste disposal system to malfunction , they did not identify which part of the process went wrong
尽管这些实验证明了朊病毒可以使废物处理系统故障，但它们并没有分辨出究竟是哪个环节出了错。 |
| 8. | By carefully measuring the rate at which proteasomes laboured , she found a clear correlation : as the clumps of prions in the sample got bigger , the proteasomes slowed down
通过测试这些水解酶的工作速率，她发现了一个清晰的关系：当标本中的朊病毒团变大时水解酶的工作便慢了下来。 |
| 9. | It was found that prion which is made up of proteins exclusively is the main cause and it has two forms , i . e , normal form prpc and abnormal one prpsc
目前已知疯牛病的致病因子是完全由蛋白质组成的朊病毒( prion ) ，它存在“正常”和“致病”两种状态，分别被称为prp ~ c和prp ~ sc 。 |
| 10. | If a drug could be made that inhibits this fragmentation process , it could substantially slow the spread of prions , which cause mad cow disease and scrapie in animals and , in rare cases , creutzfeldt - jacob disease and kuru in humans
药物可阻滞这些蛋白裂解片段过程，从而持久的减慢朊病毒传播，包括疯牛病和绵羊疯痒病和一些人类罕见疾病克-雅二氏病和库鲁病等疾病的传播。 |
