suffer many a setback during one's life; adverse fortune; be down on one's luck; very unlucky
Example Sentences:
1.
Unhappy woman she has been too long and too persistently denied her legitimate prerogative to listen to his objurgations with any other feeling than the derision of the desperate 该妇命途多舛,其合法特权屡遭践踏,时间既久,对方态度复顽强,致使伊每闻彼之斥责,辄报以由绝望而导致之嘲笑。