The mrd , firstly discovered by us with neuroanatomical and immunohistochemical methods , was a flat , pan - shaped structure at the caudomedial margin of the neostriatum and surrounding the rostrolateral edge of the globus pallidus in brains of the rat [ 12 ] , cat [ 12 ] , monkey [ 13 ] and human 研究的目的及意义:谷氨酸是哺乳类动物中枢神经系统的一种兴奋性神经递质,其受体分为离子型和代谢型两类。离子型具有完整的阳离子通道,而代谢型( mglut )则通过蛋白转到胞内信号系统而起作用。