A muscle is a very large number of fibers close together, containing two different substances myosin and actomyosin . 肌肉是由极多的彼此紧帖的纤维所组成的,它含有两种不同的物质:肌球蛋白和肌动球蛋白。
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A investigation for the directional stochastically hopping motion of myosin v 定向运动的随机跃迁动力学研究
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Studies on the mechanism of combined gelation formation of myosin and - carrageenan 卡拉胶混合胶凝机理的研究
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Effects of exercise on myosin and convertion of muscle fiber types 运动训练对肌球蛋白重链及肌纤维转型的影响
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Myosin light chain kinase 肌球蛋白轻链激酶
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Effects of 5 - azacytidine on expression of - myosin heavy chain in cultured rat bone marrow stromal cells 骨髓干细胞移植与心肌修复的相关效应
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Such filaments are usually composed of the contractile proteins actin and / or myosin , and are thought to play a role in cell motility , and perhaps also change in shape 这种丝通常由伸缩蛋白肌动蛋白和(或)肌球蛋白组成,一般而言它们在细胞运动中起一定作用,并可能改变自身的形状。
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Polymer his - tagged peac1 - gfp efficiently activated myosin mg - atpase activity , which indicated that peacl might take part in correlative living activities in vivo . moreover , this result provided experimental proof in vitro for fusing gfp to actin isoform directly to study the dynamics of microfilaments and its regulation in vivo . we prepared rabbit anti - pea actins polyclonal antibodies using peacl as antigen which being expressed and purified from prokaryotic cells , and the antibodies possessed better immunity activity to pea actins 通过肌动蛋白体外对dnase以及肌球蛋白atpase活性影响的研究,发现单体his - taggedpeac1 - gfp能显著抑制dnase活性,在肌动蛋白聚合条件下能有效激活肌球蛋白atpase活性,这一结果预示着peac1在体内可能参与相关的生命活动,为利用gfp直接与肌动蛋白异型体融合来研究体内微丝的动态变化及其调节提供了实验依据。
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The thesis includes three parts : firstly , previous study and latest advance of molecular motor in biology are outlined , including myosin ' s and kinesin ' s construction and function , the latest advance of molecular motor in constructional biology ; secondly , the latest advance of molecular motor in physics is reviewed , including the general view of brownian motor and two examples of molecular motor , one being related to two kinds of flashing potention energy , the other being related to electronical bipole ; and finally , the model on unidirectional motion of molecular motor is in detail come up with , and especially , the interact ion between two heads is taken into account , followed by the construction of langevin equation and fokker - planck equation involved in the model . by using solutions of fokker - planck equation , unidirectional motion mechanism of molecular motor is analyzed 本文内容包括:首先综述生物学领域分子马达研究的最新进展,内容安排为:肌球蛋白的结构和功能,驱动蛋白的结构和功能,肌球蛋白和驱动蛋白定向运动机制的结构生物学方面的最新进展;其次综述并分析了当前研究分子马达定向运动机制的几种物理模型,内容安排为:分子马达运动的基本观点和建构模型的一般方法,势垒的两态涨落诱导的分子马达运动模型,分子马达定向运动的偶极子模型;最后讨论双头相互作用的分子马达模型,内容安排为:先详细论述模型的构建,再建立langevin方程和fokker - planck方程,接着用差分的方法求解出fokker - planck方程的解,然后分析和研究分子马达定向运动的机制。