| 1. | This is one ick that has allowed the name to cover so much of the 13 ) globe
就是这一招让必胜客的品牌能够遍布全球。 |
| 2. | This 15 ) angered prometheus , so he ied to 16 ) ick zeus and make him look stupid
这激怒了普罗米修斯，因此他试图愚弄宙斯、让他看起来很蠢。 |
| 3. | Quantitative evaluation of left ventricular diastolic function of coronary artery disease pre - and post - intracoronary stent implantation by ick
技术评价冠心病冠状动脉支架置入术前后左心室节段舒张功能 |
| 4. | According to the sequences similarity and the same disulfide linkage of hwtx - v family with other toxins with known 3d structures , we can postulate that hwtx - v may belong to ick ( inhibitory cysteine knot ) motif
从这些同源序列的二硫键的结合方式看来， hwtx一v和mhwtx一v很可能属( 1nhibitorycysteineknot ) ick结构模体。 |
| 5. | Protein engineering studies , taking hwtx - i adopting ick structure model as a model molecule , provide important value of basic research and possess a widely applied prospect for other polypeptide neurotoxin according to document reports else
综合其它文献报道，以hwtx一i的ick结构模体为分子框架进行蛋白质工程，为其它多肤类毒素提供了重要的基础研究价值及实际运用前景。 |
| 6. | The space conformation of co - ctx mviia and hwtx - i is highly similar . both molecules contain the typical " inhibitor cystine knot motif ' ( ick ) , which is a proper molecular model for protein engineering
- ctxmv a和hwtx -两种分子的空间结构十分相似，都包含典型的“抑制剂胱氨酸结模体” ( inhibitorcystineknotmotif ， ick )结构，这是一种适合蛋白质工程改造的分子结构模型。 |
| 7. | The research of the renaturation and biological activity of the chimeras confirmed the active sites of hwtx - i and mviia further . it also indicates that the structure of ick is stable and is an ideal model molecule for protein engineering
通过对嵌合体复性和活性情况的研究，进一步证实了hwrtx一i和mvlla的活性位点;并且表明抑制剂胧氨酸结模体( ick )的结构确实是相当稳定的，是一种进行蛋白质工程的较理想的模型 |
| 8. | Its action site is located on the postsynaptic membrane and the biological activity of hwtx - i is located in the fifth p - turn containing lys25 and lys 27 . to - conotoxin mviia is a neurotoxin belonging to one of n - type ca2 + channels inhibitors , purified from the venom of the conus marine snails , contains 25 amino acid residues with three disulfide binds . it adopts the pattern of ick and its linkage of the disulfide binds and space conformation are highly similar to hwtx - i
-芋螺毒素mviia ( - conotoxinmviia )是从芋螺属( conus )海底蜗牛毒液中分离提纯的一种活性多肽，属于n -型ca ~ ( 2 + )通道阻断剂中一种，含25个氨基酸残基，三对二硫键，其二硫键连接方式、分子的空间构象与hwtx -很相似，采取ick结构模体。 |
