We used sds - page and western blot to detect a - 1b glyco - protein moleculers in culture medium . one bind was detected at mole - culer mass between 66 - 43 kda , which show a maximal level at 7 day . discussion the function of human a - 1b glycoprotein precursor gene is still not known 我们利用生长激素( gh )处理肝癌bel 7442细胞系, a ibgp的表达明显高于对照组,说明gh可以调节a ibgp的表达,该基因可能参与gh的生理功能及在与gh相关的疾病中发挥作用。