The nobel prize in physiology or medicine 1998 : robert francis furchgott 诺贝尔生理学或医学奖-罗伯佛契哥特
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The 1998 nobel prize was shared with two other american scientists , prof . robert f . furchgott and prof . louis j . ignarro , who also contributed to the early evidence that no is a normal biological regulator of blood vessels 酸作为一种讯息分子方面获颁一九九八年的诺贝尔生理学及医学奖。他与两位提出初步证据证明氧化氮是正常的血管生物调控者的美国科学家? ?罗拔
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Nitric oxide was first identified as endothelium - derived relaxing factor ( edrf ) by professor furchgott in the early eighties in the 20th century . in recent years , it was found out that no plays a great role on the forming of nociception 一氧化氮( no )最初是由furchgott教授于20世纪80年代初以内皮衍生舒张因子( edrf )的形式提出的，近年来发现它在疼痛的形成中发挥着重要的作用。
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Shortly following prof . furchgott s discovery of edrf , a vasodilator substance released from vascular endothelial cells , prof . murad s laboratory was the first to show that edrf used an identical signal transduction pathway as no to cause vasodilation , suggesting that edrf and no could be very similar ( if not identical ) molecules . a few years later , prof . ignarro and prof . furchgott confirmed that edrf was indeed no 随著富斯葛教授发现血管内皮衍生舒张因子? ?一种血管内皮细胞释放的一种血管舒张物质，短短的时间内梅里教授的实验室率先证明血管内皮衍生舒张因子与氧化氮是用相同的讯息传递途径去引致血管舒张的? ?因而引申到血管内皮衍生因子和氧化氮，如果不等同也是非常相似的分子。
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In 1980 , furchgott and his colleagues presented the first evidence that acetylcholine ( ach ) , by acting on endothelial cells , stimulated the release of a relaxing factor ( edrf ) that acted on the preconstricted rabbit thoracic aorta to produce relaxation . a research interest on the endothelium - derived regulation of vascular tone , since then , is on the increase 自1980年furchgott发现乙酰胆碱( acetylcholine , ach )可通过内皮释放一种舒张因子( edrf ) ，使预先收缩的免主动脉环松弛以来，人们对内皮源性血管张力调节机制进行了广泛的研究，现已证实， edrf便是一氧化氮( no ) 。
