English translation for "c1q"
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- 补体1q,补体第一成分的q亚成分
循环免疫复合物
- Example Sentences:
| 1. | And c1q - positive neurons . it suggests that melatonin can inhibite the generation of inflammatory factors , which may be related to the effects of melatonin on improvement of cholinergic dysfunction 免疫反应阳性细胞非常少,前者主要是星形细胞,后者主要是小胶质细胞和少量神经元。提示 | | 2. | Usually , clr is binding to c1inh ( cl inhibitor ) . when immune complex ( ic ) binds to clq , c1inh is detached form clr , and then the serine protease is activated , and then the complement classical pathway is activated 在一般情况下, c1r与c1inh ( c1inhibitor )结合着,而一旦有免疫复合物( ic )结合到c1q上时,浙江大学硕士学位论文cllnh的抑制作用即行移除, clr的构象发生改变,具有酶活性,从而启动补体激活经典途径。 | | 3. | In this study , a novel strategy to inhibit the activation of the complement system has been developed . to get the purified clq as the target molecule for biopanning , the first step of our purification was to isolate the clq from clr2cls2 by affinity chromatography on igg - sepharose 4b column 本研究另辟蹊径,以补体经典激活途径始动分子c1q为靶标,采用噬菌体肽库技术,亲和筛选能与c1q结合的噬菌体克隆,研制可抑制补体激活的c1q模拟短肽。 | | 4. | We focused on the following aspects ; 1 ) we first assayed the expression of complement receptors and complement - associated molecules on distinct subsets of dendritic cells during their development in order to understand the physical basis of the sensitivity of dendritic cells to complement and its split products ; we next studied the effects of complement activation on the survival of dendritic cells during their development ; and finally examined the effects of the whole complement system , focusing on the ability of one of the split products of complement activation , c5a , and its first subcomponent - c1q , to influence chemotaxis of dendritic cells , as well as allo - t cell stimulatory activity of dc 我们通过免疫磁珠分离了两种人dc前体,即髓系来源的单核细胞( monocytes , mo )和淋巴系来源的浆细胞样dc ( plasmaeytoiddendriticeells , pdc ) ,对这两个不同dc亚群进行体外诱导培养,使其处于不同的分化发育阶段,然后检测了其表达补体受体一cd35 ( cri ) 、 cd21 ( crz ) 、 cdilb ( cr3 ) 、 cdlle ( cr4 ) ,补体调控蛋白一cd46 、 cd55 、以及部分补体片断分子受体一c3ar 、 csar 、 clqrp的水平。 | | 5. | Activation of the complement may lead to killing of the microorganisms by direct lysis effect of complement system or the phagocytosis by the enhancement of the attachment of microbes to the phagocyte ( opsonization ) . low serun concentrations of mbl in man is the basis for a common opsonic defect associated with recurrent infection 它可选择性识别多种病原体表面的糖结构,以不依赖抗体和c1q的方式激活补体,发挥溶破和间接调理功能,还能与吞噬细胞胶凝素受体结合而起直接调理作用。 | | 6. | By elisa analysis , inhibition of binding of clq with the c ! q receptors on u937 cells and competitive inhibition of binding of clq with aggregated immunoglobulin g b y selected phage clones , and dna sequencing , a number of similar , but not identical , sets of sequences of clq - binding clones were identified . the deduced amino acid sequences of selected 9 peptides are wyegpftlytwp , hwdpfslsayfp , ltqhnspffllp , tsnpfflwypqp , qtpfqlw , npfnwts , spfxlts , fltwldp and fstflyp . they show significant efficiency to inhibit the binding of clq with the clq receptors on u937 cells and / or aggregated immunoglobulin g , which suggest that the selected peptides contain the modeling epitopes of clq receptor to bind the collage - like region or igg to bind the head domain of clq 然后,采用噬菌体肽库技术,以c1q为钓饵蛋白,从12肽库和环7肽库中亲和筛选能与c1q结合的噬菌体克隆,经elisa 、 u937细胞配体结合抑制试验、 aigg竞争抑制试验及dna测序,获得了9个具c1q抑制活性克隆的dna序列,其相应的氨基酸序列为: wyegpftlytwp 、 hwdpfslsayfp 、 ltqhnspffllp 、 tsnpfflwypqp 、 qtpfqlw 、 npfnwts 、 spfxlts 、 fltwldp 、 fstflyp ,它们可能模拟c1qr和或igg的c1q结合表位并抑制c1q的活性。 |
- Similar Words:
- "c1esterase inhibitor c1-inh" English translation, "c1inhibitor" English translation, "c1inhibitor deficiency" English translation, "c1n" English translation, "c1osed-circuit breathing apparatus" English translation, "c1q complement receptor" English translation, "c1q补体受体" English translation, "c1s" English translation, "c1s]阻滞c1s补体系统抑制剂" English translation, "c1ustered preferences" English translation
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