| 1. | Although the catalytic activity of angiogenin is rather weak , it is critical for its angiogenic properties 血管生成素的核糖核酸酶活性很弱,但对它的血管生成活性是至关重要的。 |
| 2. | Angiogenin is expressed in a wide range of different human cells . it can induce angiogenesis in pathological and perhaps normal circumstances 血管生成素在人类各种细胞中均有广泛表达,可促进正常和病理条件下血管生成。 |
| 3. | Alteration of angiogenin activity to either promote or inhibit angiogenesis could have significant therapeutic potential in angiogenesis - related diseases 促进或抑制血管生成素的血管新生活性在治疗血管新生相关疾病上具有潜在的临床应用价值。 |
| 4. | The article summarize that angiogenin of classification , physiologic function and gene structural excessively expresses in microbe and applies in physic field 本文对其分类及生理学作用,基因结构,及在微生物中的过量表达和医学领域的应用作一综述。 |
| 5. | Angiogenin ( ang ) is a small monomer which universally exists in tissues and cells . angiogenin belonging to ribonuclease superfamily has 35 % homologous sequences with ribonuclease a ( rnase a ) 血管生长因子( angiogenin , ang )是一个小的单聚蛋白,与rnasea是同系物,在组织和细胞中分布广泛。 |
| 6. | Angiogenin belongs to a protein superfamily of rnase . it is the only member being able to stimulate angiogenesis . on the other hand , angiogenin is also the only angiogenic factor known to exhibit ribonucleolytic activity 血管生成素是核糖核酸酶超家族中唯一一个具有促血管生成能力的成员,也是目前已知的所有血管生成因子中独具核糖核酸酶活性的因子。 |
| 7. | Angiogenin is very important physiologic function on normal tissue growth and rebuilding . furthermore , it possibilitily takes part in birthing new vein of the tissue of tumour , and acts the pathology in transferring tumour 摘要人血管生成素对正常机体的组织发育和再生具有较重要的生理功能,同时还可能参与肿瘤组织的新生血管生成,在肿瘤转移中发挥病理作用。 |
| 8. | It interacts with endothelial cells , mediates a number of cellular responses including cell adhesion and invasion , and is translocated to the cell nucleus where it may act on its putative rna substrate . clinical application of angiogenin is closely associated with its potent angiogenic activity 血管生成素可以作用于血管内皮和平滑肌细胞,引起一系列细胞反应,包括:促进靶细胞的增殖,诱导细胞的迁移和侵入,介导细胞粘附,还可以经内吞作用定位于细胞核,发挥其核糖核酸酶活性。 |