Objective to investigate the importance of autoimmunity against 1 - adrenoreceptor in the pathogenesis of dilated cardiomyopathy ( dcm ) 目的研究1肾上腺素能受体的自身免疫在扩张性心肌病发病中的重要作用。
2.
Rabbits in the immunized group ( n = 7 ) were immunized monthly for one year with synthetic peptide correspo nding to the second extracellular loop of the 1 - adrenoreceptor and adjuvant 用1肾上腺素能受体细胞外二环肽段和佐剂对免疫组动物进行每月一次免疫，总时程为一年。
3.
Conclusion autoimmunity against the 1 - adrenoreceptor may be involved in the pathogenes is of dilated cardiomyopathy and 1 - adrenoreceptor antibody may play a role in the process 结论1肾上腺素能受体自身免疫可能参与了扩张性心肌病的发病，而1肾上腺素能受体抗体可能在这一过程中起一定作用。
