| 1. | Aav amphibious assault vehicle 两栖突击车 |
| 2. | Aav anti afterburn valve 防止后燃阀 |
| 3. | Aav doesn ' t always insert in this particular spot , however , even when it still has its site - specific preference 然而, aav即使当它仍然具有它的位点特异偏好时,也不会总是插入这一特殊位置。 |
| 4. | But the comparison amino acid sequence shows that gpv dna has high homology with the human adeno - associated virus aav - 2 in dependovirus and b19 in erythrovirus Gpv与依赖病毒属成员aav - 2及红病毒属成员人细小病毒b19的进化关系较近。 |
| 5. | We selected a tiny virus called adeno - associated virus ( aav ) as our vector , in part because it infects human muscle readily but does not cause any known disease 我们选择腺相关病毒( aav )这种微小病毒做为载体,部份原因是它很容易感染人类肌肉,却不会引发任何已知的疾病。 |
| 6. | Comparison of vpl of gpv strain hl with other parvoviruses showed that the homology between gpv strain h1 and aav - 2 was higher than that of gpv stains h1 and other autonomous parvoviruses Gpvh1株与其他细小病毒vp1的氨基酸序列同源性比较证明gpvh1与依赖病毒aav - 2的同源性高于与自主细小病毒的同源性。 |
| 7. | Better yet , it only goes into a few specific places in the genome - - and these are not obviously as safe as the aav site , because they tend to be in the gaps in the middle of genes called introns 尤其可贵的是,它只进入基因组的少数特异位置?这些明显地不如aav位点那么安全,因为它们倾向于进入称为内含子的基因中间缝隙。 |
| 8. | The first big breakthrough in solving this problem was when it was found that one virus , the adeno - associated virus ( aav ) , preferentially inserts into a particular ( safe ) place on human chromosome 19 解决这一问题的第一个大突破,是发现一种病毒,即腺病毒相关病毒( aav ) ,会有选择地插进人类第19号染色体的一个特殊(安全)位置。 |
| 9. | The close genetic relationship of goose parvoviruse and aav allows the examination of the molecular biological properties of the nonstructural proteins of gpv . after the gpv infected the cell the viral life cycle was regulated by the nonstructural proteins encoded by the virus . according to the published of gpv b strain genome nucleotide sequences in genbank and a pair of specific primers were disigned with oligo4 . 1 本研究根据genbank发表的gpvb株全基因序列,借助oligo4 . 1软件设计一对引物,采用pcr技术扩增gpvh1株非结构蛋白ns2基因,并与pmd18 - t载体连接后测序,结果表明:鹅细小病毒h1株ns2基因核苷酸全长1356bp ,编码451个氨基酸残基,与gpvb株的ns2基因相比,核苷酸数目相同,有17个碱基、 6个氨基酸的差异;同源性分析表明:二者核苷酸序列同源性为98 . 75 ,推导氨基酸序列同源性为98 . 67 。 |