The method of concentrating the decoloration solution of tylosin is usually carried out by thin film vacuum concentration . in this experiment , the concentration process is modified by using the nanofiltration membrane technique which is free from corrosive due to the extractant solvent and in the same time , heating and decomposition of the antibiotic are eliminated , the concentration course ia also distinctly shortened . in this process the small molecule can be filtered by water , and the quality of the product such as , the tyramine content , the solubility of the product , improved significantly . in addition , the membrane filtration process could save consumption of steam and cooling water 泰乐星提炼过程中原工艺脱色液用薄膜真空浓缩，本试验改进为耐溶媒纳滤膜浓缩，料液不需要加热即可浓缩，防止了料液的高温分解破坏，浓缩收率明显提高在浓缩的同时，部分小分子杂质可以随水分子一起通过纳滤膜而除掉，成品质量明显提高，解决了用原工艺成品酪胺、溶解度不合格的质量问题省去了原工艺浓缩中费用较高的蒸汽、冰盐水，经济效益可观。
