辅助刺激信号 meaning in Chinese
costimulating signal
Examples
- Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ) , but also needs the second signal , termed costimulation . costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc
而t细胞的活化除需要t细胞受体( tcr )与抗原呈递细胞( antigenpresentingcell , apc )表面的抗原肽- mhc复合物结合所形成的第一信号外，还需要t细胞和apc表面的其它膜分子结合所提供的共刺激信号(亦称第二信号或辅助刺激信号， costimulatorysignal )的参与。