转录激活因子 meaning in Chinese
activating transcription factor
atf
stat
transcriptional activator
Examples
- Stat3 ( signal transducer and activator of transcription 3 ) is important for embryo morphogenesis , cell growth , apoptosis and cell mobility
信号转导和转录激活因子3 ( stat3 )在动物的早期胚胎发生、细胞生长、凋亡控制和细胞运动等过程中起着很重要的作用。 - To further enhance protein productivity of expression vectors , two artificial transcription activating domains , ah and vp2 , were linked to cl represser protein of phage through a soft linker , respectively , and thus two artificial transcription activators were created
为了进一步提高表达载体表达外源蛋白的能力，我们把两个人工转录激活结构域ah和vp2分别通过一个柔性的linker融合到噬菌体ci蛋白的c末端，构建了两个人工转录激活因子。 - All the components mentioned above were integrated into ped5 , producing two vectors : per - ah and per - vp2 . the two vectors were tested for their efficiency of expressing ifn - and seap reporter genes in comparison with perfrt , a vector similar to per - ah and per - vp2 except for lacking of artificial transcription activators
以ifn -和seap报告基因对其表达效果进行检测，结果per - ah表达外源蛋白的能力仅略高于perfrt (一个除了不含人工转录激活因子外，其余都与per - ah或per - vp2完全相同的载体) 。 - Notch interaction with its ligands induces the cleavage of its intracellular domain ( ic ) , and the notch ic translocates to the nucleus and binds to rbp - j , the mammalian homolog of su ( h ) , to transactivate transcription of target genes such as e ( spl ) ( enhancer of split ) , hesl ( hairy and enhancer of split ) and hes5 four notch receptors and their ligands are differentially and redundantly expressed in a variety of vertebrate tissues
它通过其识别序列（ cogtgggaa ）结合于受调控基因的启动子区，在转录激活因子的驱动下调节细胞分化和个体发育相关基因的表达。在没有n 。 tch胞内段的情况下， rbpj可与包含sm盯（ silencingmediatorforretlnoldandthyroidhormonereceptor ）和组蛋白去乙酞化酶的转录辅助抑制复合物结合，当notch信号被激活时； rbpj可与n 。 - The two single - pass transmembrane proteins , delta and serrate , have been identified as notch ligands . the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway . rbp - j , the mammalian homolog of su ( h ) , recognizes the core sequence ( c / tgtgggaa ) of dna
Rbp - j是果蝇促神经发生基因su ( h ) ( suppressorofhairless )在哺乳动物的同源物，它通过其识别序列( c tgtgggaa )结合于受调控基因的启动子区，在转录激活因子的驱动下调节细胞分化和个体发育相关基因的表达。