调控序列 meaning in Chinese
regulatory sequence
Examples
- Promotor , in broad sense , consists of transcription start site , binding site of rna polymerase ( promoter in narrow sense ) and upstream regulation sequence
广义的启动子( promotor )包含有转录起始部位、 rna聚合酶与dna结合部位(也就是狭义的启动子)以及上游调控序列。 - After a lox2272 site was added in front of the bovine - casein gene 5 ' regulatory fragment , a mammary gland universal expression vector plbcas - hsa - lgl was created
最后在-酪蛋白基因5 `端调控序列前面,连上一个lox2272位点,最终的乳腺特异性表达载体plbcas - hsa - lgl构建完成。 - One positive clone was obtained from the libraries with casein flat and electrophoresis comparison method . analyzed the sequencing result , the positive clone include the open read frame of mlap gene and upper regulatory sequence
序列测定分析表明,此重组质粒包含有长度为1377bp低温碱性蛋白酶基因的完整的开放读码框架( orf )和上游基因调控序列。 - The most efficient regulation of gene occurs at transcription level by regulating the interaction between transcription factors and upstream regulation sequence . thus , to investigate promoter of a target gene will be helpful to predicate the principle of molecule regulation , biological function of molecule and even involving pathogenesis of some diseases
转录水平是调控蛋白质表达效率最高的环节,通过影响相应的转录因子与启动子和上游调控序列的相互作用调控目的基因的表达,因此研究基因的启动子对于了解基因的表达调控规律、阐明分子的结构和生物学功能乃至疾病的发生都有重要的意义。 - Then , 5 . 5kb thrombiotin gene was amplified with the same technique from the genome of a baby ' s blood , which included the begining part of intronl to the teminator . in addition , 6 . 0kb and 1 . 8kb homlogous arms were also amplified from a cow with high yield . the 6 . 0kb homologous arm contains the promotor , extron 1 , extron2 , extron3 and intron 1 , intron2 and part of the intron3 fragment , while the 1 . 8kb homologous right arms contains exon13 , exon14 and part of intron 13 , the whole intron14 and part intron 14 of asl - casein gene of bovine
通过长片段pcr从高产奶牛的基因组中获得了打靶所需的长、短同源臂序列,长度分别为6 . 0kb和1 . 8kb ,位于s1 -酪蛋白基因的5上游区到第三内含子和十二到十四内含子;从绵羊全血基因组克隆得到了绵羊的-酪蛋白基因启动子区到第二内含子区4 . 1kb的5调控序列;利用同对引物克隆得到了水牛的同基因序列;从广西当地一婴儿脐血基因组中通过获得了人血小板生成素基因,位于第1内含子到终止子后部分的序列,长达5 . 5kb 。