补体调控蛋白 meaning in Chinese
complement control protein
Examples
- An array of regulatory proteins have been found , which inhibit the formation of central enzymes involved in early stages of the complement activation pathway . these include membrane cofactor protein ( mcp cd46 ) , decay - accelerating factor protein ( daf cd5 5 ) , complement receptor 1 ( cr1 , cd35 ) , as well as cd59 , which inhibits formation of the membrane attack complex during later stages . these regulatory factors are widely expressed and abundant on many cells , and in fluids of reproductive system
目前发现，机体多种细胞以及生殖系统的体液中表达和分泌丰富的补体调控蛋白，包括作用于补体活化早期阶段的cd55 、 cd46 、 cd35和作用于补体活化终末阶段的cd59 ，它们分别通过抑制补体活化过程中关键的c3 、 c5转化酶和抑制形成膜攻击单位，抵抗补体对自身组织细胞的攻击。 - We focused on the following aspects ; 1 ) we first assayed the expression of complement receptors and complement - associated molecules on distinct subsets of dendritic cells during their development in order to understand the physical basis of the sensitivity of dendritic cells to complement and its split products ; we next studied the effects of complement activation on the survival of dendritic cells during their development ; and finally examined the effects of the whole complement system , focusing on the ability of one of the split products of complement activation , c5a , and its first subcomponent - c1q , to influence chemotaxis of dendritic cells , as well as allo - t cell stimulatory activity of dc
我们通过免疫磁珠分离了两种人dc前体，即髓系来源的单核细胞( monocytes ， mo )和淋巴系来源的浆细胞样dc ( plasmaeytoiddendriticeells ， pdc ) ，对这两个不同dc亚群进行体外诱导培养，使其处于不同的分化发育阶段，然后检测了其表达补体受体一cd35 ( cri ) 、 cd21 ( crz ) 、 cdilb ( cr3 ) 、 cdlle ( cr4 ) ，补体调控蛋白一cd46 、 cd55 、以及部分补体片断分子受体一c3ar 、 csar 、 clqrp的水平。