膜内在蛋白 meaning in Chinese

integral membrane protein

Researches of schistosomiasis vaccines have gone more than 60 years , approximately including from the stages of dead vaccine and live vaccine ( irradiated attenuated cercariae vaccine ) to gene engineered vaccine , etc . many different forms of vaccines have been tested in animal models , including gluthathione s - transferase , paramyosin , irv - 5 , triose phosphate isomerase , sm23 , fatty acid binding protein ; which were considered promising by who / tdr . but none of them steadily accomplished the pre - set target level of 40 % protection . in order to enhance the protective capacity further , it is essential to develop novel vaccine antigens and / or vaccine adjuvants
血吸虫病疫苗研究已有60多年的历史，大致经历了死疫苗、活疫苗(照射致弱尾蚴疫苗)和基因工程疫苗等研究阶段，产生了一些who / tdr推荐认为很有希望的疫苗候选分子，如谷胱甘肽- s -转移酶( gst ) 、副肌球蛋白( sm97 ) 、照射致弱疫苗抗原5 ( irv - 5 ) 、磷酸丙糖异构酶( tpi ) 、曼氏血吸虫膜内在蛋白( sm23 )和脂肪酸结合蛋白( fabp ， sm14 )等，但其对宿主的保护作用均不甚理想，未能稳定地达到40或以上的保护力水平，因此有必要继续寻找新的疫苗抗原分子和/或疫苗佐剂，进一步提高其保护力。