翻译后修饰 meaning in Chinese
post-translation modification
posttranslational modification
Examples
- It was indicated that regulation of 20ahsd activity was not due to post - translational modification by either phosphorylation cycle or glycosylation , but rather at the transcription level of 20ahsd gene expression in previous research papers
以往研究表明20 hsd活性的调节不是通过糖基化、磷酸化或去磷酸化等翻译后修饰实现的,而是以转录水平的调节为主。 - The gpit - catalyzed reaction represents the final step in the assembly of a gpl - anchored protein , and provides the critical post - translational modification of this class of proteins that allows them to gain entry into er - derived transport vesicles for delivery to the cell surface
Gpit催化的这一反应为gpi化蛋白生物合成的最后一步,也是关键的一步。此翻译后修饰过程保证了这类蛋白质进入出自于er的转运囊泡,再被传送至细胞表面。 - Currently there are many techniques available to screen the gene expression at the transcriptional levels , such as mkna differential display and cdna microarray . although these methods can provide high - throughput information about the differential gene expression , they can
虽然,利用mrna差异显示技术和基因芯片技术可在转录水平高通量的筛选基因表达的差异,但是这些技术都不能提供转录后的尤其是蛋白质在翻译后修饰的信息,而蛋白质通常是细胞内的功能执行者。 - The quickly developing techniques of biological mass spectrometry ( bio - ms ) in recent years realized the high throughput identification of proteins by determining the accurate mass values of trypsin - digested peptides and the randomly selected peptide sequence tags , and have been successfully used in the studies of protein interactions and post - translational modification such as the phosphorylation
摘要近几年快速发展起来的生物质谱技术,依靠(酶解后肽段)精确质量数测定和随机肽序列标签分析,实现了对蛋白质高通量的鉴定,并被成功地用于蛋白质相互作用和蛋白质磷酸化等翻译后修饰研究。 - We found that there are two types of map1lc3 in rat , mouse and human , besides that , there is another type ( map1lc3c ) in human . we expressed all map1lc3 in hek293 cells respectively and found that the post translational modification of all map1lc3 is similar to yeast apg8 and rat map1lc3 identified except human lc3b . characteristic carboxyl cleavage occurred in conserved glycine of them
在hek293细胞中分别表达这三个物种中的所有的a型、 b型以及人map1lc3c分子,发现除了人的map1lc3b外其它同源物的修饰方式与已知的酵母apg8和大鼠的lc3修饰方式相类似,均发生了羧基端的切割反应而且羧基端保守的甘氨酸是它们发生翻译后修饰的活性位点。