大挫折 meaning in Chinese

blooper

When anything goes this well, a major setback can be just around the corner .
一件事过于顺利的时候，很可能不久就会有大挫折。
But i have had a bad setback
可是我遭受了一次大挫折。
To see his season disrupted by injury was a big blow but there were some obvious highlights , not least doing the double over old rivals liverpool with the last - gasp win at anfield a real moment to savour
他的赛季被伤病打断是个大挫折，但是还是有不少闪光时刻，特别是最后时刻双杀死敌利物浦最令人回味。
Regrettably , i learnt from other delegates that a newly established overseas anti - graft agency had suffered serious setbacks as it had aroused public dissatisfaction due to a lack of effective checks on its powers
会上亦听闻有一新成立的海外反贪机构，因为权力缺乏制衡，而令其职能备受公众质疑，结果反贪的工作受到很大挫折。