卵成熟 meaning in Chinese
maturation of ovum
ovum maturation
Examples
- Fully grown xenopus oocytes can remain in their immature state essentially indefinitely , or , in response to the steroid hormone progesterone , can be induced to develop into fertilizable eggs . this process is termed oocyte maturation
介绍:爪蟾卵在成熟过程中可以无限期的停留在未成熟状态,直到在激素的刺激下,成为可受精的卵细胞,这个过程称为卵成熟。 - These feedback mechanisms often make it difficult to determine the order of e - vents in a signalling cascade , since a small level of mpf activity is sufficient to activate most of the pathways involved in oocyte maturation
但是,这样的反馈增加了对爪蟾卵成熟过程的调控机制探索的困难,反馈的存在使得人们不能确定信号传导的顺序。在反馈网络中,很难决定激酶的上下游关系。 - An important feature of meiotic maturation is an extensive network of feedback signalling ( mostly downstream of mpf activation ) , which is responsible for the generation of an all - or - none response ensuring that the oocyte completes meiotic progression
总的来说,爪蟾卵成熟过程受到复杂的相互作用的激酶网络的调节,这样的反馈网络使得爪蟾卵成熟成为一个“ all - or - none ”的过程。 - The model may be used not only to simulate the process , but also to provide explanations why the process is so ; here we give an explanation of such a process . we showed that pka increased the threshold 0 our model might be used to simulate and explain the normal oo - cyte maturation process , and next , we simulated several experiments and compare results observed in our simulation with those observed in experiments . quantitative models could be well used to simulate kinase activity changes in xenopus oocyte maturation
模型可以用来模拟这样的卵成熟的过程,也就说明了这个模型在一定程度上是符合卵成熟过程的真实情况的,但是,如果仅仅是模拟,发挥不出模型的真正作用,模型的作用是让人们在模拟这样的卵成熟过程的同时,通过这样的一个模型工具深人的理解卵成熟的机制我们通过对模型进行分析发现: pka可以升高mpf激活的总的cyclinb阈值,从而使卵停留在gz期 - Free cyclin level is low for they quickly bind with cdc2 , the total cyclin mainly exist in mprty ( pre - mpf ) ml to m2 process ; all the elements are set to g2 arrest concentration , then we set pka - > ipka rate = 0 . 1 to simulate progesterone effect , ( it has been reported that progesterone can decrease the camp level , thus causes pka inactivation ) mpf activity rise at ml , falls at the inter phase between ml and m2 , and then remains high at m2 arrest
: 22 nxm m dt ‘ ? ? “ ? ‘民十cd 。 251 i : vj rccjc25 pi然后,我们应用gepasi来进行这个模型的计算机模拟结果爪群卵成熟过程的模型模拟gz期阻滞,总的cyclinb的含量虽然升高,但是mpf保持在低活性状态,随着pka的失活, mpf活性有戏剧性的变化,它的活性在mi升高,在问期下降,然后又在mz期升高,最后停留在高活性的mz期。