减毒株 meaning in Chinese
attenuated strain
Examples
- However , the homologies of g and n gene between wild strains and attenuated strain ctn are much high
三株野毒与减毒株ctn之间的n和g基因同源性均高于与3ag 、 era株的同源性。 - G gene of rabies virus m , the of two main regions ( about 1000nt ) , ranging from 3161nt to 4162nt and ranging from 4012nt to 4863nt of glycoprotein gene of rabies virus strain m , isolated from mouse in he nan , china were amplified by reverse transcriptase - polynerase chain reaction ( rt - pcr ) in order to complete glycoprotein gene of strain m . these regions were sequenced by the produce of pcr directly . comparison and analysis of nucleotide sequence and amino acid sequence deduced with that of other strains published was performed by computer with dnasisv 2 . 5demo software
本研究对我国河南某地野鼠体内分离的狂犬病野毒株mrv基因的3161位? 4162位( 1001个碱基)和4012位? 4863位( 851个碱基)片段进行了反转录pcr扩增和序列测定，得到mrv的糖蛋白基因全序列，用dnasisv2 . 5demo分析软件，与已发表的代表性毒株g基因全序列进行核苷酸和氨基酸序列的比较分析，结果表明在同一基因型中， mrv和国际标准攻毒株cvs的同源性最高( 96 . 5 ) ，和中国减毒株ctn的同源性最低( 79 . 8 ) 。 - Strain mrv and strain cvs are belong to the same genotype . however , strain mrv , ctn and cnx8511 are belong to different sub - genotype . finally , this researched also proved that the character of neuron tropism rabies viruses by comparison and analysis the homologies of amino acid sequence between 189 - 214 position and the bonding segment of snake venom curaremimetic neurotoxims and acetylcholine
从计算机建立的各毒株系统树分析， mrv和cvs属于一个基因亚型，和我国减毒株ctn以及人源野毒株cnx8511属于不同的亚型，并且证明了189 - 214位氨基酸序列与蛇神经毒素同乙酰胆碱结合部位的序列具有高度的同源性，说明狂犬病病毒的嗜神经特点。