免疫刺激复合物 meaning in Chinese
immune-stimulating complexes
immunostimulating complex
is-com
iscoms
Examples
- This modification includes : ( 1 ) selecting two important molecules as candidates , ( 2 ) choosing a promiscuous t - cell epitope , and two b - cell epitopes or conserved amino acid sequences from the two important molecules , ( 3 ) connecting them adequately through analysis by the molecule designing software . therefore , the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing . based on the molecule designing methods , the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse , as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected
本研究以蛋白质分子设计的理论和方法研究避孕疫苗，将sp17和cyritestin关键表位和牛核糖核酸酶非选择性th细胞表位合理组合，获得新抗原- 35肽序列；并在合成、纯化后分别与弗氏佐剂、免疫刺激复合物( iscoms )混合后免疫不同遗传背景的雌性小鼠，观察血清和生殖道内的特异性抗体滴度的动态变化、生育力的改变以及免疫后小鼠重要脏器的组织病理学改变：以及在ivf下，新抗原的特异性抗血清对精卵相互作用的影响及抗原在精子表面的特异性定位。 - The major outer membrane proteins ( momps ) of an aeromonas hydrophila named ahl316 which isolated from diseased eel and the referential strain ahtps - 30 were purified and used for preparing immunostimulating complexs ( momp - iscoms ) . the immunotrial was carried out by injecting european eel peritoneally with 20ug of momp - iscoms per eel
本研究选取鳗源嗜水气单胞菌l316和参考菌株嗜水气单胞菌tps - 30 ，分别制备了这两株菌主要外膜蛋白免疫刺激复合物( momp - iscoms ) 。 - Make all these together , it proved that the cloned gene represented the major outer membrane protein gene of ahl316 , and the expressed gene products shared identical antigenicity with the natural main outer membrane protein . the studies on preparation and application of momp - iscoms of ah l316 provided a new approach to fish vaccinology . the successfully cloning and expressing the major outer membrane protein gene of ah l316 made it possible to describe this gene ' s function under a single factor level , and also provided technical support for developing an advanced gene engineering vaccine and subunit vaccine against aeromonas hydrophila
鳗源嗜水气单胞菌l316主要外膜蛋白免疫刺激复合物的制备与应用研究，对研制鱼类疫苗学问题进行了新的初步探索；成功地克隆和表达嗜水气单胞菌l316主要外膜蛋白基因为在单因子水平上研究嗜水气单胞菌外膜蛋白的作用和免疫功能以及制备嗜水气单胞菌基因工程疫苗和亚单位疫苗奠定技术基础。