做出很大的努力 meaning in Chinese

make a good effort

Requires a significant effort in term of toxity testing
对于毒性测试，需要做出很大的努力
Her grandmother , paula , a milliner by trade , who kept up with old nazi friends long after the war , " must have had to make great efforts not to know anything " of her brother - in - law ’ s activities
凯特琳的祖母保拉是一个女帽商，她在战争结束之后很长一段时间还和自己的纳粹老朋友保持联系，她“肯定曾经不得不做出很大的努力，不去了解”自己二伯的任何活动。
Since the 1980 ' s , we have taken great effort to modify the classroom instructional model to promote students development , but on the whole , we still can not construct an effective instructional model which enables students to wholly develop their quality as well as their creative and productive ability
自八十年代以来，我国基础教育的课堂教学模式改革虽然在促进学生发展方面已做出很大的努力，但就整体而言，尚未构建出一种使学生的素质得到全面发展，创新精神和创新能力都得到加强的新的教学模式。