中子俘获治疗 meaning in Chinese
neutron capture therapy
Examples
- Neutron capture therapy ; liposome ; gadolinium complex ; tumor cell
中子俘获治疗脂质体钆配合物癌细胞 - Transport of liposome as a carrier for gadolinium neutron capture therapy
脂质体作为钆中子俘获治疗肿瘤药物载体的 - Kinetics and mechanism study of across - membrane transport of liposome as a carrier for gadolinium neutron capture therapy
脂质体作为钆中子俘获治疗肿瘤药物载体的跨膜动力学及机理研究 - Liposome is an effective nuclide delivery agent for neutron capture therapy . in this paper liposomes containing encapsulated gadolinium complex were prepared and characterized . the influence of formulation factors such as ph , ionic strength , buffer , and storage time upon the stability of liposomes was investigated . the uptake rate constant and its concentration dependence of lgd in tumor cells were compared in vitro with that of gd complex itself . the results indicate that the uptake rate of lgd in tumor cells increases to eight times as much as that of gd - edta , but the release rate of gd from tumor cells containing lgd is remarkably lower than that from the tumor cells containing gd - edta . the results reveal that lgd would be a potential drug for neutron capture therapy of cancer
制备和表征了包埋gd - edta的脂质体，测定了ph ，离子强度，缓冲液组成及温度对gd - edta脂质体的影响，比较了gd - edta脂质体和gd - edta被肿瘤细胞摄入的动力学曲线。结果表明， gd - edta脂质体在37和生理条件下最稳定，肿瘤细胞摄入gd - edta脂质体速率是gd - edta的8倍，而释放gd的速率， gd - edta脂质体远远低于gd - edta ,这些结果提供了脂质体包埋gd - edta作为钆中子俘获治疗药物的可能性。