t细胞免疫 meaning in Chinese
t cell-mediated immunity
Examples
- Dendritic cells ( dc ) are the most potent professional antigen - presenting cells ( apc ) , required for the initiation of immune response . for all that the mechanism of dc functions are not fully elucidated
树突状细胞( dendriticcell ， dc )是一种重要的专职抗原提呈细胞( apc ) ，具有刺激初始型t细胞增殖、启动初次免疫应答的独特功能，是t细胞免疫应答的直接启动者和调控者。 - Up to now , clinical trails have been conducted in u . s . a . and europe to observe the antitumor effects of exosomes . exosomes may be a kind of potential vaccines for tumors in future . on the other hand , exosomes may be a kind of tolerogenic materials
为此，我们以一种c57bl / 6来源的3lllewis肺癌细胞系建立模型，用3ll细胞系和3ll肿瘤组织分泌的exosomes进行了体内和体外的功能实验，并从t细胞免疫应答的角度初步探讨了其作用的机制。 - Dendritic cells are characterized by their ability to efficiently present antigen , and are uniquely equipped to stimulate naive t cell responses . immature dendritic cells acquire antigens from throughout the peripheral body , then migrate to t - lymphocyte - dependent areas of lymph nodes . thus , dendritic cells act as bridges , operating at the interface of innate and acquired immunity
作为机体免疫系统中功能最强的专职性抗原提呈细胞( antigen - presentingcells , apc ) ，树突状细胞( dendriticcells , dc )能高效地摄取、加工处理和提呈抗原，具有较强的迁移能力，并能显著地激活初始型t细胞以启动t细胞免疫应答反应，此外， dc与b细胞以及nk细胞等也存在着相互作用，可见， dc在连接天然免疫和获得性免疫之间起着非常重要的作用。 - Dcs play a pivotal role in the development of antitumor immunity . t lymphocytes immune response induced by direct antigen - pulsed dcs can not maintain longer for peptides - mhc department or mhc molecules degeneration . the method of dcs loading with tumor antigen gene is another potential approach to enhancing and maintaining immune response
在用抗原直接刺激dc时，由于抗原- mhc复合物解离或细胞mhc分子降解而不能维持所诱导的t细胞免疫应答，借助载体把肿瘤抗原基因导入dc后肿瘤抗原在dc内的持续表达能增强其抗原提呈能力并能维持所诱导的免疫效应。