multimer meaning in Chinese
多体
Examples
- In the wild type hasnpv bvs , no detectable multimer was found . however , in the pseudotyping baculovirus bvs , three oligomer bands were found besides
在hasnpvbv中没有发现ha133的多聚体,然而该重组病毒bv中却有三种ha133的多聚体存在。 - Conclusion : it ' s possible to improve the expression efficiency by adjusting the g + c content of tir region and codon usage . replacement the cystein 78 and cystein 96 into serines , higher bioactivity gained compared with control hbfgf protein , and decreased amout of dimer and inclusion body , this suggested that free thiol group of cys78 and cys96 is the main reason of dimer and multimer formation
结论:通过调整tir区g c含量及增加大肠杆菌偏爱的密码子,确实能提高hbfgf在大肠杆菌中的表达量,而将78和96位上的半眯氨酸替换成丝氨酸后,得到的hbfgf的蛋白活性高于未改构蛋白,二聚体和包涵体减少。 - Objectives : in our previous study , to improve the expression efficiency of human basic fibroblast growth factor ( hbfgf ) expressed in escherichia coli , we lowered the g + c content in hbfgf ' s tir region and used more preferred codons by e . coli . meanwhile we found the low insoluble product with a large quantity of dimer and higher multimer in the protein solution . it greatly decrease the bioactivity of hbfgf
目的:我们在长期实践中发现,大肠杆菌中表达的人碱性成纤维细胞生长因子( humanbasicfibroblastgrowthfactor , hbfgf )在e . coli中表达量不高,可溶性低,蛋白溶液中大量存在二聚体,三聚体以至多聚体,使得hbfgf的生物活性大大降低。