misshape meaning in Chinese

vt.
弄丑，使残废；使破相。

The place that some bacteria can misshape via a priori ( if the skin antrum of lumbar di ministry ) cause meningitis break out repeatedly
有的细菌可经先天畸形的部位（如腰骶部的皮肤窦道）引起脑膜炎的反复发作。
But after bleeding for many times , articulatory and intumescent tenderness , the activity suffers be restricted , misshape to joint eventually rigidity , sweeny and function are lost
但多次出血后，关节肿大压痛，活动受限，终至关节畸形强直，肌肉萎缩和功能丧失。