homodimerization meaning in Chinese
均二聚
Examples
- Gfral is an extracellular protein that is attached to the outer cell membrane by gpi - anchor and could not transducted signalling directly . according to the original model , a gdnf dimer first binds to either monomeric or dimeric gfral , and the gdnf - gfral complex then interacts with two ret molecules , thereby inducing their homodimerization and tyrosine autophosphorylation
传统观点认为: gdnf首先与gfr 1结合形成gdnf - gfr 1复合物,此复合物再与ret结合形成三聚体复合物,引起ret的二聚化,并引起酪氨酸残基自磷酸化,从而引起下游的信号转导。