gpi-anchor meaning in Chinese

糖基磷酯酰肌醇锚区

Preparation of mb7 . 1 - gpi - anchored tumor vaccine and its antitumor effect
1融合蛋白的制备及抗肿瘤作用研究
Gfral is an extracellular protein that is attached to the outer cell membrane by gpi - anchor and could not transducted signalling directly . according to the original model , a gdnf dimer first binds to either monomeric or dimeric gfral , and the gdnf - gfral complex then interacts with two ret molecules , thereby inducing their homodimerization and tyrosine autophosphorylation
传统观点认为： gdnf首先与gfr 1结合形成gdnf - gfr 1复合物，此复合物再与ret结合形成三聚体复合物，引起ret的二聚化，并引起酪氨酸残基自磷酸化，从而引起下游的信号转导。
Many glycoproteins of lower and higher eucaryotes are attached to the plasma membrane by means of a glycosylphosphatidylinositol ( gpi ) . gpi - anchored proteins are synthesized on membrane - bound ribosomes . upon translocation of the pro - protein across the endoplasmic reticulum membrane , gpi : protein transamidase ( gp1t ) recognize and removes the carboxy terminal gpi signal sequence and attaches a gpi molecule to the newly exposed carboxy terminal amino acid
Gpi化前体蛋白在依附于膜的核糖体上合成，当其易位穿过内质网( er )膜后，被gpi ：蛋白质转酰胺基酶( gpit )识别， gpit在移走其羧基端gpi信号序列的同时将gpi分子连接至新生成的氨基酸位点上。