costimulation meaning in Chinese
共同刺激
Examples
- Effect of cd86 costimulation on the modulation of th1 th2 cytokines expression at maternal - fetal interface
2型细胞因子表达调控中的作用 - Influence of blockade of cd86 costimulation on th1 th2 cytokines transcription at materno - fetal interface and outcomes of pregnancy
2型细胞因子转录调控及妊娠结局的影响 - It has been demonstrated that b7 - cd28 pathway is a prominent costimulation pathway which leads full t cell activation , induces differentiation and regulates the production of cytokines . lacking and blocking of b7 - cd28 pathway will result in blockage of the t cell activation and proliferation
研究表明b7 - cd28通路是最主要的刺激t细胞活化的共刺激信号通路，其不仅参与t细胞活化过程，还影响活化后t细胞的分化、细胞因子产生等。 - Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ) , but also needs the second signal , termed costimulation . costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc
而t细胞的活化除需要t细胞受体( tcr )与抗原呈递细胞( antigenpresentingcell , apc )表面的抗原肽- mhc复合物结合所形成的第一信号外，还需要t细胞和apc表面的其它膜分子结合所提供的共刺激信号(亦称第二信号或辅助刺激信号， costimulatorysignal )的参与。