blys meaning in Chinese
激活因子
Examples
- The b lymphocyte stim lator ( blys ) also known as baff , tall - 1 , thank , ztnf4 , is the most recent addition to the tumor necrosis factor family ( tnf ) ligands . blys induces both in vivo and in vitro b cell proliferation , differentiation and immunoglob lin secretion . meanwhile , it also strongly suppresses the growth of tumor cell lines . the over - production of blys is associated with the development of certain autoimmune disease , such as systemic lupus erythaematosus ( sle ) , rheumatoid arthritis , myasthenia gravis , sj greh ' s syndrome
人b淋巴细胞刺激因子( hblys )是1999年发现的肿瘤坏死因子超家族成员。最早发现其可诱导肿瘤细胞凋亡，之后发现它是一个强有力的b细胞共刺激因子，它在体外及转基因动物体内可明显刺激b细胞的生长，免疫球蛋白分泌，并导致动物自身免疫性改变。 - Therefore , blys , its receptor or related antagonists may find medical utility in the treatment of b cell disorders associated with autoimmunity , neoplasia , or immunodeficiency syndromes . in this study , epo signal peptide sequence and hsblys gene were linked by soe method . the fusion product was cloned into eukaryotic plasmids . pcdna3 , pcdna3 . 1 , pefneo , respectively . meanwhile , the epo signal peptide sequence was mutated so as to form a restriction enzyme cut site : bin i . thus the recombinant plasmid can be used as secreting plasmid expressing other gene
本实验通过3 ’端互补，进行引物延伸合成epo信号肽序列：信号肽和hsblys基因采用重叠延伸拼接法形成融合基因；融合基因分别插入pcdna3 . 0 、 pcdna3 . 1 、 pefneo真核载体：引物延伸合成信号肽时，利用亮氨酸同义密码，将信号肽基因的倒数第二个密码突变，在重组载体上的信号肽序列之后，形成bln酶切位点，使三种载体成为分泌表达载体。