On closer inspection , early ischemic enteritis involves the tips of the villi 早期的局部缺血性肠炎肠绒毛近距离检查。
2.
There is blunting and flattening of villi with celiac disease , and in severe cases a loss of villi with flattening of the mucosa as seen here 脂痢病肠绒毛变扁平，严重病例黏膜扁平、绒毛缺失，如右图所示。
3.
The histologic lesions were characterized by the remarkable atrophy of intestinal villi , basal vacuolation of enterocytes , increment of the crypt and the villus - to - crypt ratio had significantly decrease . compared with that of noninoculated control chicks . besides . intestinal villi become thin and flat . or cubic , also accompanied with necrosis . many villous enterocytes were detached from the lamina propria and the lamina propria contained a diffuse infiltrate of lymphocytes , plasma cells , macrophages . the characteristic ultrastructural changes observed by electronmicroscope were swelled mitochondria and dilated endo - plasticreticulum . ribosome on the surface of endo - plasticreticulum fall off and the number of ribosome within the cell decrease 动物回归试验中接种两周龄spf鸡， 24h后陆续发病，表现为持续性水样腹泻；剖检可见病鸡脱水、小肠内有大量的液体和气泡、肠粘膜变薄；组织学变化为肠绒毛上皮坏死、脱落，绒毛平均长度减少而隐窝深度增加，固有层中淋巴细胞浸润。其临床症状及病理组织学变化与自然发病相同。
